Brian Skotko, MD, MPP
Estimation of the number of people with Down syndrome in the United States
Estimation of the number of people with Down syndrome in the United States
Genet Med. 2016 Sep 8. doi: 10.1038/gim.2016.127. [Epub ahead of print]
An accurate accounting of persons with Down syndrome (DS) has remained elusive because no population-based registries exist in the United States. The purpose of this study was to estimate this population size by age, race, and ethnicity. Until 2008, DS was a rare disease. In more recent decades, the population growth of people with DS has leveled off for non-Hispanic whites as a consequence of elective terminations. Changes in childhood survival have impacted the age distribution of people with DS, with more people in their fourth, fifth, and sixth decades of life.
Estimation-of-the-number-of-people-with-Down-syndrome-in-the-United-States.pdf