CGM Genotyping Resource
- Director: Marcy MacDonald, Ph.D.
- Team Leader: Tammy Gillis
Services:
Custom mutation detection/DNA sequencing, dosage analysis, Custom genotyping (microsatellite, SNP, other), in human and mouse, Other services related to genetic analysis
CGM DNA and Tissue Culture Resource
- Director: James Gusella, Ph.D.
- Senior Technician: Jayla Ruliera
Services:
Buffy coat storage, DNA extraction from blood and cell lines, Fibroblast culture service, Lymphoblast transformation service, Plasma isolation service, Tissue culture service
CGM Clinical Genetic Research Facility
- Director: James Gusella, Ph.D.
- Senior Genetic Counselor and Senior Program Manager: Diane Lucente, M.S.
- Clinical Research Coordinator II: Alexandra Silva
Services:
Genetic counseling and consultation, Professional services are available on a per-hour basis., Includes assistance with genetic consent forms, Grant assistance, A Grant Advisor is available for consultation on a per-hour basis, Outpatient study support
Facility provides access to:
* 6 exam rooms
* 2 interview/observation rooms
* A phlebotomy room
* A sample processing laboratory and short-term freezer storage
* Various lab prep services, including experienced and enthusiastic personnel to take vital signs, perform phlebotomy, and blood processing
CGM Microscopy Resource
- Director: Susan Cotman, Ph.D.
- Resource manager: Uma Chandrachud, Ph.D.
Equipment offered:
Leica SP5 AOBS Scanning Laser Confocal Microscope equipped with 5 lasers, two HyD adapters for improved speed and sensitivity on two of the detectors, and a Super Z-galvonized imaging stage for rapid z-section imaging; equipped for fixed cell, live cell and whole mount imaging needs
Zeiss upright standard epifluorescence microscope equipped for digital image capture
Nikon inverted standard epifluorescence equipped for digital image capture, microinjection, and live cell imaging.
Olympus light microscope equipped for digital image capture
CGM Administrative Core
- Core Manager: Ryan Sullivan
- Operations Manager: James Mull
- Facilities coordinator: Chris Kelleher
- Administrative assistant: Shannon Stratton
Serves an administrative function to assist investigators and the CGM research staff in managing facilities, and general administrative support.
The Center for Genomic Medicine (CGM) comprises one of the largest and most vibrant hubs of genomic medicine research in the world. The CGM includes 46 faculty collaborating to define the ‘genomic medicine cycle’ – which envisages a genomics community seeking to advance research from basic genomics research to ultimately using genome information for diagnostics and targeted therapeutics. All of our investigators are faculty at Harvard Medical School, and many members of our community are also investigators at the Broad Institute of Harvard and MIT.
