Focus Areas in the Genomic Medicine Cycle
Major leadership positions

Director of Research, Learning and Emotional Assessment Program

MGH Department/Division

Psychiatric & Neurodevelopmental Genetics Unit | Child Psychiatry

MGH Unit(s)

Psychiatry | Center for Genomic Medicine

Overview

We study neuropsychiatric illness and related outcomes across the lifespan.

Our research aims to promote a better understanding of the development of neuropsychiatric illness across the lifespan by investigating risk mechanisms, phenotypic variation, and moderators of youth trajectories. We have a particular interest in how genetic influences and cognitive capacities contribute to risk and resilience and whether these constructs can be leveraged in the clinical setting to improve patient outcomes. We use various strategies (genomics, cross-diagnostic traits, and computational approaches) to study psychopathology predictors and correlates that may be targets for intervention. This work seeks to lay the foundation for improved diagnostics, evidence-based assessment, risk stratification, and personalized care.

Priority Projects

  1. Translating genomic discoveries to the child psychiatry clinic: Polygenic risk scores as objective indicators and tools for risk stratification
  2. Genomic and phenotypic correlates of suicidal thoughts and behaviors in children and adolescents
  3. Leveraging genomics to clarify the relationship between cognition, ADHD and functional outcomes across the lifespan
  4. Understanding the relationship between genomic variation and psychiatric comorbidity

Lab Members

Name:Email:Role:
Pieter J Vuijk PhDPVUIJK [@] mgh.harvard.eduStaff scientist/ biostatistician
Maya KovenMKOVEN [@] mgh.harvard.eduClinical Research Coordinator
Lauren Fleminglfleming11 [@] mgh.harvard.eduClinical Research Coordinator
Lauren WolfeLEWOLFE [@] mgh.harvard.eduClinical Research Coordinator
Phoebe Parkerpparker3 [@] mgh.harvard.eduClinical Research Coordinator
Lab/Contact Telephone

617-724-1531

Primary Email

doylea [@] helix.mgh.harvard.edu