Focus Areas in the Genomic Medicine Cycle
Major leadership positions
Investigator, Howard Hughes Medical Institute
Institute Member, Broad Institute
MGH Department/Division
Molecular Biology
MGH Unit(s)
Mitochondrial Medicine Unit
Overview
The long-term goals of the Mootha Laboratory are to combine the new tools of genomics and systems biology with classic biochemistry to investigate mitochondrial bioenergetics, evolution, and disease.
Priority Projects
- Diversity of the mitochondrial proteome across organs and organisms.
- Investigating mtDNA variation: from single-cells to biobank-scale
- Harnessing hypoxia as a novel therapeutic approach to mitochondrial disease
- Developing new genetic tools for investigating energy metabolism
Lab Members
| Name: | Email: | Role: |
|---|---|---|
| Fanny Ng | MGH Lab Manager | |
| Naomi Ostriker | Broad Lab Manager | |
| Bryanna Vacanti | Grant Administrator |
Lab/Contact Telephone
617-643-9710
Primary Email
vamsi [@] hms.harvard.edu
The Center for Genomic Medicine (CGM) comprises one of the largest and most vibrant hubs of genomic medicine research in the world. The CGM includes 46 faculty collaborating to define the ‘genomic medicine cycle’ – which envisages a genomics community seeking to advance research from basic genomics research to ultimately using genome information for diagnostics and targeted therapeutics. All of our investigators are faculty at Harvard Medical School, and many members of our community are also investigators at the Broad Institute of Harvard and MIT.
