Clinical Research Coordinator II-Scharf Lab

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The Scharf Laboratory in the Center for Genomic Medicine at Massachusetts General Hospital (MGH) is seeking a motivated, enthusiastic candidate to join our research group. Our research group in the Center for Genomic Medicine and the Departments of Neurology and Psychiatry investigates genetic and non-genetic risk factors for Tourette syndrome (TS) and related conditions, such as obsessive-compulsive disorder (OCD) and attention deficit hyperactivity disorder (ADHD). In addition to the work we do locally, our group co-leads national and international multi-center genetic and phenotypic analyses of TS and related disorders.


We enroll patients from our clinic as well as from across the nation to participate in our research studies. In addition to collecting DNA and biological samples (e.g., skin biopsy tissue) from study participants, we collect extensive phenotypic information. This includes diagnostic assessments of neurodevelopmental and psychiatric conditions as well as medical, social, and family histories. One current study for which we are currently recruiting is a collection of blood and skin biopsies from patients with TS and/or OCD to generate patient-specific iPSCs and patient-specific neurons that we can then use to examine the effects of genetic perturbations in the lab. In addition to these collections, we utilize online survey-based methods using REDCap—a secure, web-based application. For those interested in or who have experience with statistics, there are additional opportunities to be involved with statistical genetics projects or the analysis of survey data.


We are presently seeking a highly-motivated individual to fill a Clinical Research Coordinator II (CRC II) position beginning in May/June of 2019. The standard responsibilities of a CRC II are outlined below. However, additional duties and responsibilities may be required. This is an excellent opportunity for those interested in pursuing medical school or a PhD in clinical psychology, and affords numerous opportunities for exposure to neurology, psychiatry, and neuropsychiatric genetics. We hope that our research will inform and improve future diagnostic, prognostic, and treatment and prevention strategies for these conditions. For more information about our research and our group, please visit our websites: (PNGU) and (Center for Genomic Medicine)


Please note, the functions below are representative of major duties that are typically associated with these positions. Specific responsibilities may vary based upon departmental needs. Similarly, not all duties that have been outlined will be assigned to each position.  



  • Collects & organizes patient data
  • Maintains records and databases
  • Uses software programs to generate graphs and reports
  • Assists with recruiting patients for clinical trials
  • Obtains patient study data from medical records, physicians, etc.
  • Conducts library searches
  • Verifies accuracy of study forms
  • Updates study forms per protocol
  • Documents patient visits and procedures
  • Assists with regulatory binders and QA/QC procedures
  • Assists with interviewing study subjects
  • Administers and scores questionnaires
  • Provides basic explanation of study and in some cases obtains informed consent from subjects
  • Performs study procedures, which may include phlebotomy.
  • Assists with study regulatory submissions
  • Writes consent forms
  • Verifies subject inclusion/exclusion criteria
  • Performs administrative support duties as required


A Clinical Research Coordinator II performs the duties of a Clinical Research Coordinator I (above) and may also:

  • Maintain research data, patient fields, regulatory binders and study databases
  • Perform data analysis and QA/QC data checks
  • Organize and interpret data
  • Develop and implement recruitment strategies
  • Act as a study resource for patient and family
  • Monitor and evaluation lab and procedure data
  • Evaluate study questionnaires
  • Contribute to protocol recommendations
  • Assist with preparation of annual review
  • May assist PI to prepare complete study reports



  • Careful attention to details
  • Good organizational skills
  • Ability to follow directions
  • Good communication skills
  • Computer literacy
  • Working knowledge of clinical research protocols
  • Ability to demonstrate respect and professionalism for subjects’ rights and individual needs


The Clinical Research Coordinator II should also possess:

  • Ability to work independently and as a team player
  • Analytical skills and ability to resolve technical problems
  • Ability to interpret acceptability of data results
  • Working knowledge of data management program



Bachelor’s degree required.



New graduates with some relevant course/project work or those without any prior research experience will be considered for the Clinical Research Coordinator I position outlined above.

Those with a minimum of 1-2 years of directly related work experience will be considered for a Clinical Research Coordinator II position.



A Clinical Research Coordinator I does not have any supervisory responsibility.

A Clinical Research Coordinator II may assist with the training and orientation of new staff members.

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