Program Manager, Technology Operations – CGM – (3210667)

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The Center for Genomic Medicine (CGM) comprises one of the largest and most vibrant hubs of genomic medicine research in the world. The CGM includes over 50 full-time faculty collaborating to define the ‘genomic medicine cycle’ – which envisages a genomics community seeking to advance research from basic genomics research to ultimately using genome information for diagnostics and targeted therapeutics. The Cycle is a paradigm that begins by discovering genetic variants that contribute to phenotypic differences between individuals, then progresses to characterizing the mechanisms by which underlying DNA differences lead to disease and is then completed when the knowledge gained delivers benefit back to patients in the form of diagnosis and/or treatment. The CGM is recruiting an individual who will play an integral role in the genomic medicine cycle, by maintaining the technologies and equipment infrastructure within the CGM that are critical to the research activities of the labs.

The Technology Operations Program Manager will ideally have 5+ years of experience in technology implementation in genomics research in academia or industry. The Technology Operations Program Manager reports to the CGM Director and CGM Associate Director, and is responsible for collaborating with CGM laboratories to facilitate their use and implementation of a sophisticated battery of CGM equipment for state-of-the-art genomics research. The CGM infrastructure that falls under the purview of the Program Manager consist of (but not limited to): molecular technologies such as mass spectrometry (GC- and LC-MS systems), protein and nucleic acid quantification and sequencing (Illumina MiSeq, 10x Genomics Single Cell, AxioScan Jess automated western blotting, real time PCR, and digital droplet PCR), high content and real-time microscopy (Incucyte SX5 and InCell Analyzer 6000), robotics

(CyBio-Well Vario), cell culture technologies (Amaxa and Lonza Nucleofectors), and physiology (Seahorse XF96). The Technology Operations Program Manager will collaborate at a high level with all CGM groups wanting to use this equipment, in the process facilitating training, use (via standardized protocols), and standard operation and maintenance of these technological CGM resources.

Benefits to the successful applicant will include generous salary commensurate with experience, ability to learn and optimize scientific technique on a diverse array of technologies, potential for academic collaboration with CGM mechanistic laboratories, and potential for inclusion on scientific publications and grants for an enterprising, ambitious candidate.




We are looking for a flexible, entrepreneurial self-starter who takes initiative, is passionate about continuous learning, and is excited by new technology-driven solutions in biomedical research and genomics. The ideal individual will have experience in technology implementation in research and thrive in an environment where job duties will evolve as technology implementation and use shifts in the Center. The recruit for this position has the potential to contribute to many important research projects and programs across our Center.


  • Facilitates use of complex CGM equipment amongst CGM laboratories and users, making use of and optimizing standard operating procedures (SOPs).
  • Responsible for maintenance and troubleshooting of CGM equipment and infrastructure.
  • Develops and optimizes SOPs for CGM infrastructure based upon experience and use.
  • Helps to develop systems to schedule and track use of CGM equipment and infrastructure.
  • Ensures that proper training is administered prior to use of complex and expensive CGM equipment by users. Assures that staff adheres to proper methodologies and ongoing training and certification requirements.
  • Coordinates preventive maintenance and repairs; helps to identify parties responsible for funding repairs based upon use of equipment.
  • Integrates new equipment into CGM infrastructure and deprioritizes equipment that is not used frequently or broadly enough to justify Center-level support.
  • Opportunity to contribute to scientific publications, grants, and have authorship on CGM publications.
  • Management and supervision of all aspects of the technical and support operations of the CGM to ensure investigator satisfaction, efficient workflows and quality services.
  • Oversees inventory management as it relates to consumables necessary for the proper operation of CGM equipment. This includes purchase orders, shipping, receiving, packaging, replacement, and advanced replacement.
  • Provides direct feedback to the CGM Associate Director and Administrative Director on use of equipment, any misuse by trained or untrained individuals, improvement in operating procedures, and suggestions for incorporation of new technologies into the CGM infrastructure.
  • Manages special projects as identified by the CGM Director
  • Identifies, proposes, and implements solutions related to problem solving
  • Performs other duties as assigned and remains flexible on changing scope of duties in time.
  • The Technology Operations Program Manager will liaise directly with the CGM Facilities Manager on issues of maintenance, repair, and purchase.




  • Strong problem-solving skills
  • Strong interpersonal and management skills, comfortable in a multidisciplinary setting
  • Executive and senior level verbal and written communication skills
  • Strong time management skills
  • Flexibility and a willingness to perform a variety of tasks
  • Able to openly discuss plans and timelines with CGM staff to ensure reasonable expectations are set and achieved.
  • Ability to articulate CGM infrastructure offerings to CGM investigators via speaking, writing, presentation and other means.
  • Ability to effectively supervise others and provide constructive criticisms on experimental approach.
  • Excellent organizational skills
  • Attention to detail
  • Aptitude for technical problem solving
  • Ability to make independent, effective decisions
  • Computer Skills required, including the Internet, Microsoft Office, and the ability to learn and master additional skills, including the use of specialized software needed to run CGM equipment. Prior experience with diverse laboratory equipment of many different types will give the candidate a distinct advantage.









  • Bachelor’s Degree required; Advanced degree (M.S. or Ph.D.) preferred.




  • 5+ years of experience with sophisticated laboratory equipment, with a demonstrable ability to pick up additional skill sets quickly. Familiarity with genomics technologies, molecular biology, biochemistry, microscopy, and cell biology, required.
  • Ability to navigate diverse software packages and familiarity with diverse operating systems (Windows, Mac OS, and Linux) required.
  • The candidate will be considered a collaborator on CGM projects, and there will be opportunity for scientific authorship if justified; thus, scientific writing skill is preferred for publication and required for production of SOPs and scientific protocols.




Although some training of others in laboratories wishing to conduct experiments on CGM equipment, the Operations Manager will not be responsible for directly supervising any FTEs except during their time on CGM equipment/infrastructure.




The Operations Manager is responsible for managing inventory, and the execution of service contracts and instrument repairs, but otherwise has no budget center responsibilities.




Supporting 50+ independent research programs including ~400 full-time staff within a vibrant, 24/7/365 research environment. Most work will require on-site activity in the MGH main campus, though some activities (e.g. computational analyses and trainings) may be conducted remotely. Occasional travel to vendor events and training seminars may be required.

EEO Statement Massachusetts General Hospital is an Equal Opportunity Employer.  By embracing diverse skills, perspectives and ideas, we choose to lead. Applications from protected veterans and individuals with disabilities are strongly encouraged. 

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