GENERAL SUMMARY/ OVERVIEW STATEMENT:
The Mouro Pinto Laboratory in the Center for Genomic Medicine at Massachusetts General Hospital (MGH) is seeking a motivated, enthusiastic candidate to join our research group. Our research group has strong interest in rare neurodegenerative genetic disorders, particularly those caused by unstable microsatellite repeats, such as Huntington’s disease (HD) and Friedreich Ataxia (FA). A major focus of our research has been the characterization of the mechanisms responsible for repeat instability, in the context of such diseases and as potential therapeutic targets.
PRINCIPAL DUTIES AND RESPONSIBILITIES:
- Prepares basic solutions and performs base-level procedures as assigned (i.e. – pipetting, cell and tissue culture, etc.)
- Maintains laboratory notebook
- Understands and applies basic scientific techniques
- Conducts analysis of results and may begin interpretation of results
- Sets up and prepares routine experiments as directed
- Prepares lab reagents, chemicals, instruments and equipment
- May perform independent literature searches
- Assists with organizing materials for publication or presentation
- Maintains and orders supplies
- Assist with mouse colony maintenance
A Research Technician II performs the duties of a Research Technician I (above) and may also:
- Execute protocols of non-routine experiments
- Assist the PI(s) with determining the most suitable methodology
- Perform basic design and modification of protocols
- Calculate, transcribe and analyze data
- Prepare and present reports
- Organize and summarize acquired data, using scientific and statistical techniques.
- Organize and/or draft material for the preparation of research papers, manuscripts and other documents for publication and/or presentation.
- Participate in the design of experiments or field work.
- Basic molecular biology techniques (e.g. DNA extraction, PCR, gel electrophoresis)
- Mouse handling skills and dissections
- Ability to work independently and as a team member
- Good communication skills
- Computer literacy
- Ability to perform multiple tasks independently
The Research Technician II should also possess:
- Advanced molecular biology techniques (e.g. preparation of Next Generation Sequencing libraries, qPCR)
- Analytical skills and the ability to resolve technical problems
- Ability to interpret acceptability of data results
- Working knowledge of data management programs
- Demonstrated competence in research techniques and methodologies
- Bachelor’s degree required.
- New graduates with some lab experience (via course work, internships, etc.) or those without any prior research experience will be considered for the Research Technician I position outlined above.
- Those with a minimum of 1 year of directly related work experience will be considered for a Research Technician II position.
EEO Statement Massachusetts General Hospital is an Equal Opportunity Employer. By embracing diverse skills, perspectives and ideas, we choose to lead. Applications from protected veterans and individuals with disabilities are strongly encouraged.