The Grishchuk Laboratory in the Center for Genomic Medicine at Massachusetts General Hospital (MGH) is seeking a motivated, enthusiastic candidate to join our research group. Our research group focuses on the neurobiology and therapy development for the lysosomal storage disorder mucolipidosis type VI. Our current efforts are on developing AAV-based gene therapy for treatment of mucolipidosis type IV, pre-clinical testing of this approach in the mouse model, biomarker discovery.
PRINCIPAL DUTIES AND RESPONSIBILITIES:
*Prepares basic solutions and performs base-level procedures as assigned (i.e. pipetting, cell and
tissue culture, etc.).
*Maintains laboratory notebook.
*Has understanding of molarity.
*Conducts analysis of results, and may begin interpretation of results.
*Sets up and prepares routine experiments as directed.
*Prepares lab reagents, chemicals, instruments and equipment.
*May perform independent literature searches.
*Assists with organizing materials for publication or presentation.
*Maintains and orders supplies.
*Executes protocols of non-routine experiments.
*Assists PI with determining the most suitable methodology.
*Performs basic design and modification of protocols.
*Calculates, transcribes and analyzes data.
*Prepares and presents reports.
*Organizes and summarizes acquired data, using scientific and statistical techniques.
*Organizes and/or drafts material for the preparation of research papers, manuscripts, or other documents for publication and/or presentation.
*Participates in the design of experiments or field work.
*May develop modifications of existing assay techniques, experimental protocols, or new
*Synthesizes and interprets results.
*Prepares written and/or verbal status reports.
*Uses statistical and graphic summaries.
*Orients and trains new Research Technicians and Fellows.
SKILLS/ABILITIES/COMPETENCIES REQUIRED: Must be realistic, objective, measurable and related to essential functions of this job.
* Excellent communication skills
* Sound interpersonal skills and the ability to supervise others
* Ability to work independently and display initiative to introduce innovations to research study
* Ability to prepare/monitor budgets
* Ability to identify problems and develop solutions
*Ability to prioritize tasks and set deadlines
*Functions with speed, precision and an understanding of theory behind tests and procedures.
EDUCATION: BA/BA Required
EXPERIENCE: Requires 3+ years of directly related and progressively more responsible experience.
SUPERVISORY RESPONSIBILITY (if applicable): May supervise Laboratory Assistants, Technicians and Technologists.
WORKING CONDITIONS: LaboratoryApply online here: https://partners.taleo.net/careersection/ghc/jobdetail.ftl?job=3101627