The Research Technologist will work under the general direction of the PI Dr. Catarina Silva and Laboratory Director, Dr. Stephen J. Haggarty. This person is expected to efficiently support the lab’s efforts in conducting cutting-edge research in the fields of neuroscience, human stem cell biology and chemical biology, including engaging in highly collaborative projects both internally within MGH and externally. The research efforts will contribute to ongoing projects focused on the study of neurodegenerative disease mechanisms (tauopathies) and drug discovery.
PRINCIPAL DUTIES AND RESPONSIBILITIES:
- Supports and performs all activities involved in cell culture maintenance and cell-based drug screening assays
- Performs in vitro studies, including biochemical and molecular biological assays
- Assists in various laboratory techniques to help standardize, streamline, and maintain conformance of activities, in particular protein characterization methods and cell culture techniques
- Helps with maintaining inventory of and preparation of assay- and project-related reagents
- Assists in developing new and improved methods and assays for efficiently addressing research goals.
- Designs, executes, documents and interprets research experiments and results.
- Contributes in a consistent manner to experimental progress reports, grant applications, peer-reviewed manuscripts, and presentations at scientific forums.
- Attention to detail, consistency and regulated methodologies, and ability to work collaboratively in a dynamic, fast paced, team-oriented environment.
- Expected to maintain intellectual and interactive curiosity and commitment to research with appropriate reading or learning of new skills.
- Provide guidance and training in specialized procedures and use of lab equipment
- Bachelor with 2+ years of experience in a research-related field that includes cell culture experience.
- Experience with cell culture (experience in stem cell biology is preferred but not required).
- Experience in cellular (e.g., immunofluorescence, microscopy) and biochemical assays (e.g., western blotting, RT-PCR) preferred.
- Demonstrated ability to work independently and productively, with detailed note taking necessary.
- Ability to multi-task and work with deadlines is required.
- Strong organizational and analytical skills, with demonstrated ability to problem solve desired.
- Ability to work both independently and as a team member
Center for Genomic Medicine, MGH Main Campus
185 Cambridge Street, Boston 02114
Massachusetts General Hospital is an Equal Opportunity Employer. By embracing diverse skills, perspectives and ideas, we choose to lead. Applications from protected veterans and individuals with disabilities are strongly encouraged.