Huntingtin turnover: modulation of huntingtin degradation by cAMP-dependent protein kinase A (PKA) phosphorylation of C-HEAT domain Ser2550
Your Content Goes Here Huntington's disease (HD) is [...]
Long-term effects of l-serine supplementation upon a mouse model of diabetic neuropathy
Your Content Goes Here Deoxysphingolipids (1-deoxySLs) are neurotoxic [...]
Heterozygous mutations in SOX2 may cause idiopathic hypogonadotropic hypogonadism via dominant-negative mechanisms
Your Content Goes Here Pathogenic SRY-box transcription factor [...]
Proteasomal pathway inhibition as a potential therapy for NF2-associated meningioma and schwannoma
Your Content Goes Here Neurofibromatosis 2 (NF2) is [...]
CHIPping away at cardiovascular disease
Your Content Goes Here Clonal hematopoiesis of indeterminate [...]
Development of an oral treatment that rescues gait ataxia and retinal degeneration in a phenotypic mouse model of familial dysautonomia.
Your Content Goes Here Familial dysautonomia (FD) is [...]
Association of Soluble ST2 With Functional Outcome, Perihematomal Edema, and Immune Response After Intraparenchymal Hemorrhage
Your Content Goes Here This manuscript builds on [...]
Uridine and RNA as energy
Your Content Goes Here To identify genes and [...]
Clonal haematopoiesis and risk of chronic liver disease.
Your Content Goes Here Through advances in population-based [...]
Nucleosides Associated With Incident Ischemic Stroke in the REGARDS and JHS Cohorts
Your Content Goes Here This manuscript is the [...]
The Center for Genomic Medicine (CGM) comprises one of the largest and most vibrant hubs of genomic medicine research in the world. The CGM includes 46 faculty collaborating to define the ‘genomic medicine cycle’ – which envisages a genomics community seeking to advance research from basic genomics research to ultimately using genome information for diagnostics and targeted therapeutics. All of our investigators are faculty at Harvard Medical School, and many members of our community are also investigators at the Broad Institute of Harvard and MIT.
