Precision and Genomic Medicine Journal Club

The Mass General Brigham Training Program in Precision and Genomic Medicine hosts a journal club at which postdoctoral fellows and faculty discuss recent research articles covering the full spectrum of precision and genomic medicine. The Journal Club provides a great opportunity to stay abreast of cutting-edge research, connect fellows and expert faculty, and learn from each other.

Journal Club is open to postdoctoral fellows in the research laboratories of our T32 faculty as well as others by request.

Format: For each journal club, a fellow will present an original article related to precision/genomic medicine. The fellow will be paired with a faculty discussant expertise relevant to the article presented. The T32 PIs (Jordan Smoller and Heidi Rehm) are available to assist fellows in identifying and engaging faculty discussants if needed. After presenting the target article, the fellow will pose discussion questions to the faculty discussant who will then provide his/her insights, followed by open discussion.

*Refreshments will be served*

 Day and Time: Tuesdays 8 – 9 am

 Location:  MGH, Simches Research Building, 185 Cambridge St, Room 3-120 (unless otherwise specified)


Upcoming Journal Clubs:

Date Article Presenter Discussant(s)
January 21, 2020 Genomic Relationships, Novel Loci, and Pleiotropic
Mechanisms across Eight Psychiatric Disorders
Wei Zhou, PhD

Neale/Daly Lab

Jordan Smoller, MD

Professor of Psychiatry at HMS, and Professor in Epidemiology at the Harvard T.H. Chan School of Public Health

ScD; Phil Hyoun Lee, PhD

Assistant Professor of Psychiatry, HMS


Click here for article 


February 4, 2020

A Genetic Variant Associated with Five Vascular Diseases Is a Distal Regulator of Endothelin-1 Gene Expression

Click here for article


David Chiang, MD, PhD

McRae Lab

Rahul Deo MD, PhD

Associate Professor, UCSF School of Medicine
March 3, 2020 A clinically applicable approach to continuous
prediction of future acute kidney injuryClick here for article
Yi-Han Sheu, MD, ScD Tian Ge, PhD

Assistant Professor of Psychiatry, HMS

April 7, 2020  




May 19, 2020 Modeling sporadic ALS in iPSC-derived motor
neurons identifies a potential therapeutic agentClick here for article



Christiano Alves, PhD Clotilde Lagier-Tourenne M.D., Ph.D.Associate Professor of NeurologyHealey Family

ALS Endowed Chair for ResearchMassachusetts General Hospital and Harvard Medical School

Associate Member at the Broad Institute