Focus Areas in the Genomic Medicine Cycle
Major leadership positions
Director, MGH Center for Quantitative Health
MGH Department/Division
Psychiatry
Overview
Our lab focuses on developing clinical and genomic predictors of treatment response, and on developing novel therapeutics based on cellular models of brain disease.
We use cellular modeling, transcriptomics, clinical phenotyping, and small molecule screening to study psychiatric disorders including schizophrenia, bipolar disorder, and depression. We aim to provide critical resources for the neurobiological community, with high-dimensionality data extending a fully annotated and shareable biobank of patient and healthy control cells.
Lab Members
| Name: | Email: | Role: |
|---|---|---|
| Hana Yeh, PhD | Postdoctoral Research Fellow | |
| Laura Domenech Salgado, PhD | Postdoctoral Research Fellow | |
| Rose De Guzman, PhD | Postdoctoral Research Fellow | |
| Youngjung Rachel Jim, MD, PhD | Psychiatrist |
The Center for Genomic Medicine (CGM) comprises one of the largest and most vibrant hubs of genomic medicine research in the world. The CGM includes 46 faculty collaborating to define the ‘genomic medicine cycle’ – which envisages a genomics community seeking to advance research from basic genomics research to ultimately using genome information for diagnostics and targeted therapeutics. All of our investigators are faculty at Harvard Medical School, and many members of our community are also investigators at the Broad Institute of Harvard and MIT.
