Powerful, scalable and resource-efficient meta-analysis of rare variant associations in large whole genome sequencing studies
Your Content Goes Here Meta-analysis of whole genome [...]
About CGM Admin
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Mono- and biallelic variant effects on disease at biobank scale
Your Content Goes Here Identifying causal factors for [...]
Polygenic architecture of rare coding variation across 394,783 exomes
Your Content Goes Here Both common and rare [...]
Multivariate genomic architecture of cortical thickness and surface area at multiple levels of analysis
Your Content Goes Here Recent work in imaging [...]
Polygenic risk score-based phenome-wide association study identifies novel associations for Tourette syndrome
Your Content Goes Here Tourette Syndrome (TS) is [...]
Polygenic Scores Help Reduce Racial Disparities in Predictive Accuracy of Automated Type 1 Diabetes Classification Algorithms
Your Content Goes Here In a study, led [...]
A cross-disorder dosage sensitivity map of the human genome
Your Content Goes Here Large copy number variants (CNVs) [...]
Whole genome sequence analysis of blood lipid levels in >66,000 individuals
Your Content Goes Here A team of CGM investigators [...]
The Gene Curation Coalition: A global effort to harmonize gene-disease evidence resources
Your Content Goes Here Documenting the evidence supporting the [...]
Large-scale sequencing identifies multiple genes and rare variants associated with Crohn’s disease susceptibility
Your Content Goes Here Genome-wide association studies (GWASs) have [...]
The Center for Genomic Medicine (CGM) comprises one of the largest and most vibrant hubs of genomic medicine research in the world. The CGM includes 46 faculty collaborating to define the ‘genomic medicine cycle’ – which envisages a genomics community seeking to advance research from basic genomics research to ultimately using genome information for diagnostics and targeted therapeutics. All of our investigators are faculty at Harvard Medical School, and many members of our community are also investigators at the Broad Institute of Harvard and MIT.
