Diverse data expand what’s known about IBD genetics
Inflammatory bowel diseases (IBDs) are globally prevalent and heavily influenced by genetics, but the majority of genetic data collected about them have come from people of European ancestry. CGM faculty member, Hailiang Huang, describe the largest IBD genetics study to date in East Asian populations. Their data revealed 80 new IBD-associated genetic loci just in people from East Asia, and 320 loci when analyzed together with data from European individuals. The team also constructed a new, more accurate polygenic score for IBD risk.
Read more in Nature Geneticsand GenomeWeb.
The Center for Genomic Medicine (CGM) comprises one of the largest and most vibrant hubs of genomic medicine research in the world. The CGM includes 46 faculty collaborating to define the ‘genomic medicine cycle’ – which envisages a genomics community seeking to advance research from basic genomics research to ultimately using genome information for diagnostics and targeted therapeutics. All of our investigators are faculty at Harvard Medical School, and many members of our community are also investigators at the Broad Institute of Harvard and MIT.
