A team of CGM investigators and colleagues led by Pradeep Natarajan uncovered new genetic mechanisms for plasma lipid alterations using whole genome sequencing. The group expanded the allelic heterogeneity of lipids across diverse populations missed by current imputation methods. This work uncovered a new rare non-coding variant model of hyperlipidemia using new methods.
Read more in Nature Communications
The Center for Genomic Medicine (CGM) comprises one of the largest and most vibrant hubs of genomic medicine research in the world. The CGM includes 46 faculty collaborating to define the ‘genomic medicine cycle’ – which envisages a genomics community seeking to advance research from basic genomics research to ultimately using genome information for diagnostics and targeted therapeutics. All of our investigators are faculty at Harvard Medical School, and many members of our community are also investigators at the Broad Institute of Harvard and MIT.
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