Dr. Scharf is a behavioral neurologist and human geneticist whose lab uses genetic and clinical research tools to identify the underlying cause(s) and pathogenesis of Tourette Syndrome (TS) and related developmental neuropsychiatric disorders (OCD, ADHD, ASD).  By discovering individual susceptibility genes, characterizing the overall genetic architectures of these disorders, and integrating genetic data with in-depth clinical and genome biology information, we aim both to identify novel treatment targets and ultimately to predict patient-specific disease course and treatment response.